Methyl pyrrolidin-2-ylacetate

Methyl pyrrolidin-2-ylacetate - Names and Identifiers

Name	(R)-Methyl 2-(pyrrolidin-2-yl)acetate
Synonyms	Methyl pyrrolidin-2-ylacetate methyl (2R)-pyrrolidin-2-ylacetate (R)-Methyl 2-(pyrrolidin-2-yl)acetate (R)-METHYL 2-(PYRROLIDIN-2-YL)ACETATE 2-pyrrolidineacetic acid, methyl ester 2-(2-pyrrolidinyl)acetic acid methyl ester (R)-tert-Butyl 2-(2-Methoxy-2-oxoethyl)pyrrolidine-1-carboxylate tert-butyl (2R)-2-(2-methoxy-2-oxoethyl)pyrrolidine-1-carbox ylate 2-Pyrrolidineacetic acid, 1-[(1,1-dimethylethoxy)carbonyl]-, methyl ester, (2R)-
CAS	132482-05-4
InChI	InChI=1/C7H13NO2/c1-10-7(9)5-6-3-2-4-8-6/h6,8H,2-5H2,1H3/t6-/m1/s1

Methyl pyrrolidin-2-ylacetate - Physico-chemical Properties

Molecular Formula	C12H21NO4
Molar Mass	243.3
Density	1.006g/cm³
Boling Point	190.215°C at 760 mmHg
Flash Point	68.84°C
Vapor Presure	0.548mmHg at 25°C
Storage Condition	2-8°C
Refractive Index	1.44

Methyl pyrrolidin-2-ylacetate - Introduction

Methyl (R)-2-(2-pyrrolidinyl) acetate, also known as (R)-2-(2-pyrrolidinyl)ethyl methyl carbonate, is an organic compound. Its chemical formula is C9H15NO3 and its molecular weight is 185.22.

Nature:
Methyl (R)-2-(2-pyrrolidinyl) acetate is a colorless liquid with an aromatic odor. It is soluble in organic solvents such as ether and chloroform, but insoluble in water.

Use:
Methyl (R)-2-(2-pyrrolidinyl) acetate is commonly used as a catalyst and reagent in chiral analysis and chiral synthesis. It can be used for asymmetric synthesis and stereoselective reactions in drug synthesis. In addition, it can also be used for protecting group reactions in organic synthesis.

Preparation Method:
Methyl (R)-2-(2-pyrrolidinyl) acetate can be prepared by reacting pyrrolidine with methyl (2R)-bromoacetate under basic conditions.

Safety Information:
Methyl (R)-2-(2-pyrrolidinyl) acetate is generally a low-toxic compound under conventional operating conditions, but it is still necessary to pay attention to safe use. Wear appropriate personal protective equipment to avoid skin contact and inhalation. Seek immediate medical help if touched or taken by mistake. At the same time, the relevant safety operation procedures should be observed to ensure good ventilation in the laboratory.

Last Update：2024-04-09 20:52:54